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A War of Multiple Fronts: How to Fight Duchenne
By Alex Neupauer, Genetics and Genomics, ’23 Author’s Note: As a Genetics and Genomics major and a person with Duchenne muscular dystrophy (DMD), I was compelled to write a review on how to alleviate the suffering imposed by this devastating genetic disease. I consulted various scholarly articles and interviewed five experts on DMD. Approaches to […]
The Gut Microbiome and Obesity
By Lazer Introlegator, Neurobiology, Physiology, and Behavior, ’23 Author’s Note: Ever since I learned about the existence of the microbiome, I have been fascinated. When Dr. Brenda Rinard assigned my UWP102B class (Writing in the Biological Sciences) the task of writing a formal scientific literature review on a topic of our choosing, I knew that […]
The Effects of Ozone on Plant-Pollinator Interactions
By Hanna Francis, Biological Sciences ’22 Author’s Note: I grew interested in plants through botany and plant biochemistry courses at UC Davis and learned about insects while volunteering at the Bohart Museum of Entomology on campus. After taking a course about the toxicology of air pollutants, which focused primarily on human health outcomes, I began to […]
A Review of Recent Research into Remote Control of Stem Cell Differentiation through Light
By Jacob Pawlak, Biochemistry and Molecular Biology ’23 Author’s Note: I wrote this piece to bring attention to the exciting new field of research being conducted primarily in China that aims to control the differentiation of stem cells by irradiating them with different wavelengths of light. This non-invasive method is potentially of great value to those […]
Smoking Cigarettes as a Potential Mechanism in Developing Alzheimer’s Disease
By Barry Nguyen, Biochemistry and Molecular Biology ‘23 & Vincent Tran Neurobiology, Physiology, and Behavior ‘23 Authors Note: During my study abroad in South Korea, I was taken back by the number of people smoking cigarettes in the streets. As a country that valued health and beauty, I was surprised by the frequent sights of […]
Reviewing Methods of Studying Epigenetic Drift in Monozygotic Twins
By Pranjal Verma, Neurobiology, Physiology, and Behavior ‘25 Introduction Twin births made up 3.11% of American live births in the year 2020 [1]. There are two types of twin pairs: monozygotic (MZ), or those consisting of identical genomes, and dizygotic (DZ), or those consisting of genomes with 50% similarity (the same as siblings) [2]. […]
Safety and Efficacy of CAR-T cell therapy for Refractory or Relapsed B-cell Acute Lymphoblastic Leukemia
By Palak Arora Author’s Note: I wrote this review article because it was an assignment for me, for the course UWP102B. We were instructed to choose any topic from the field of biology which presented me with a wide range of possibilities. I was not sure where to begin my search but one day while […]
Identifying R loops with DNA/RNA ImmunoPrecipitation sequencing technology
Aditi Goyal, Genetics & Genomics, Statistics ‘22 Abstract: Non-Beta structures are nucleic acid structures that do not follow the classic beta-helix structure described by James Watson, Francis Crick, and Rosalind Franklin [1]. R loops are a class of non-B structures and are estimated to occur across 5 percent of the human genome [1]. R […]
Mitochondrial Dysfunction and Alzheimer’s Disease
By Nathifa Nasim, Neurobiology, Physiology, and Behavior ‘22 Author’s note: Based on my interest in exploring Alzheimer’s pathology, I have been interested in the molecular mechanisms that drive neurodegeneration. After working on a project on mitochondrial blockers and Alzheimer’s disease at the Jin lab at the MIND Institute, I found numerous intersections between neurodegeneration and mitochondrial […]
The Role of Microglia in the Two Hallmarks of Alzheimer’s Pathology
By Nathifa Nasim, Neurobiology, Physiology, and Behavior ‘22 Author’s note: While in the Jin lab at the MIND Institute, I was introduced to the intersection between inflammation and neurodegeneration, specifically in the context of Alzheimer’s disease. My interest in this relationship has primarily been in manipulating inflammatory pathways to investigate the effects on the disease. However, […]