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A Review of Personalized Cystic Fibrosis Treatments: Genotype-Phenotype Relationships
By Daniel Erenstein, Neurobiology, Physiology, and Behavior, ‘20
Author’s Note: One of the major assignments in my Writing in Science (UWP 104E) course was a literature review on some current topic of scientific interest. The process involved in understanding prior research on a topic and in predicting a field’s future directions was challenging. Along the way, I often found myself lost in a world of complicated scientific jargon. In the end, it was a personal story that provided the inspiration I needed for this article. Worldwide, more than 70,000 people have cystic fibrosis, and there are over 30,000 patients in the United States alone. Mary Frey is one of them, and she chronicles her life alongside Peter, her husband, and Ollie, her service dog, in daily vlogs on their YouTube channel. With “The Frey Life,” I was reminded that scientific research, which might sometimes seem removed from the realities of life, should be rooted in the spirit of helping people. This message guided and energized my research on cystic fibrosis. I thank Dr. Brenda Rinard for her valuable instruction, which shaped this review article throughout the writing process.