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The multi-functional protein kinases: ATM and ATR
By Carly Cheung, Microbiology, ‘17
Author’s Note:
“The goal of this paper is to portray the multifunctionality of proteins involved in the cell and how interconnected one process is to another, even though two processes appear to be unrelated. I am fascinated by the system of signal transduction in our cells and admire how elaborate and complicated the network is. This is best shown by examining the two proteins, ATM and ATR, that are known for their functions in cell cycle regulation and DNA break repair. The paper explores the changes in their transduction pathways seen in mammals with cancer, metabolic diseases, and cardiovascular diseases.”