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Feeding 8 Billion People: Engineering Crops for Climate Resiliency
By Shaina Eagle, Global Disease Biology ’24 Feeding the world’s 8 billion– and growing– people [2] is an Augean task that requires cooperation between farmers, scientists, government agencies, and industry stakeholders across the globe. Agriculture and climate are deeply intertwined and climate conditions play a critical role in determining agricultural productivity and have a significant […]
Genetic algorithms: An overview of how biological systems can be represented with optimization functions
By Aditi Goyal, Genetics & Genomics, Statistics ‘22 Author’s Note: As the field of computational biology grows, machine learning continues to have larger impacts in research, genomics research in particular. Genetic algorithms are an incredible example of how computer science and biology work hand in hand and can provide us with information that would otherwise […]
Pharmacogenomics in Personalized Medicine: How Medicine Can Be Tailored To Your Genes
By: Anushka Gupta, Genetics and Genomics, ‘20 Author’s Note: Modern medicine relies on technologies that have barely changed over the past 50 years, despite all of the research that has been conducted on new drugs and therapies. Although medications save millions of lives every year, any one of these might not work for one person […]
CRISPR Conundrum: Pursuing Consensus on Human Germline Editing
By Daniel Erenstein, Neurobiology, Physiology, and Behavior, ‘21 Author’s Note: In November 2018, a scientist in China became the first person to claim that they had edited the genes of human embryos carried to term. Two twins, named with the pseudonyms Lulu and Nana, were born from these very controversial experiments. This news rapidly propelled […]
Applications of Machine Learning in Precision Medicine
By Aditi Goyal, Statistics, Genetics and Genomics, ‘22 Author’s Note: I wrote about this topic after being introduced to the idea through a speaker series. I think the applications of modern day computer science, genetics and statistics creates a fascinating crossroads between these academic fields, and the applications are simply astounding. Next Generation Sequencing […]
Stem Cells: Miracle Cure or Hoax? A Review of Present Application and Potential Uses of Stem Cells
By Vita Quintanilla, Genetics 23’ Author’s Note: My purpose in writing this piece is to educate the current safe applications of stem cell as misuse and damage due to the same is so prevalent in the US and abroad. While not detracting from the great advances being made in the field currently this piece is to […]
You might have to use more than a microscope, there’s more to genetics than what meets the eye: An interview with Dr. Gerald Quon
By Tannavee Kumar, Genetics & Genomics 20’ Author’s Note: As an undergraduate studying genetics and genomics and computer science, I wanted to interview a former professor to find out the steps he took in order to do computational research in the biological sciences. I was interested in finding out more about the growing field of computational […]
Reading into the Future: Development of Long-read DNA Sequencing
By Aditi Goyal, Genetics and Genomics, ‘22 At this moment, the next revolution in the field of biology is currently underway: third-generation sequencing, or Long-Read sequencing. Instead of relying on cluster-based short read technology (1), third-generation sequencing builds a DNA sequence on a nucleotide basis, therefore eliminating the extensive process of read alignment. Until now, scientists across […]
CRISPR/HDR Platform Allows for the Production of Monoclonal Antibodies with the Constant Region of Choice
By Sharon Yang, Cell Biology, ‘20 Author’s Note: I first came across an article talking about this new innovation on Science X. Having worked with hybridomas and antibodies through various internships, I was deeply intrigued by this discovery and secured an original paper to learn more about its potential applications. Because of the revolutionizing usage […]
The Effect of Trastuzumab on HER2-Signaling in Breast Cancers to Induce Cardiotoxicity
By Karissa Cruz, B.S. Biochemistry and Molecular Biology, Spring ‘19 Author’s Note: I wrote this piece as part of my UWP 104F assignments and ended up becoming really interested in what I wrote about. I specifically chose this topic because I think breast cancer is a smart, complex disease, and the treatment can change day-to-day. […]