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Prenatal Exposures and Risk for Chronic Diseases Later in Life

February 26, 2014 / Leave a comment

By Marisa Sanchez, Genetics ’15

Most people know that poor diet, lack of exercise, and smoking as an adult can increase the risk of developing cardiovascular disease (CVD) and Type II diabetes. However, research over the past couple of decades has shown that risk for CVD and type II diabetes could begin as early as prenatally through adverse exposures, such as overnutrition and placental insufficiency. Some mechanisms involved in determining risk for CVD and Type II diabetes are oxidative stress, inflammation, lipotoxicity, and epigenetics. (more…)